Skin Care Benefits of TETRAPEPTIDE-21

Skin Care Benefits of TETRAPEPTIDE-21

Skin Care Benefits of TETRAPEPTIDE-21

As we get older, our skin is going through wear and tear that results in wrinkles and age spots. Although many peptides have been developed for skin care, a cosmetic peptide called TETRAPEPTIDE-21 contains loads of protein that can battle the effects of aging skin.

TETRAPEPTIDE-21 restores the dermal matrix by stimulating the body’s own collagen production and its ability to repair and renew skin. An extensive study was performed to see the effects of TETRAPEPTIDE-21 on the skin.

The following are the skincare benefits of TETRAPEPTIDE-21 derived from the study.

Boosts ECM Proteins

TETRAPEPTIDE-21 contains human extracellular matrix (ECM) proteins which are present on our skin. As we age, ECM proteins are degraded.

TETRAPEPTIDE-21 contains around 30 tetrapeptide motifs which are abundant in different ECM proteins.

TETRAPEPTIDE-21 can be great for the skin by stimulating ECM resynthesis.

Collagen Protein Production

A study was performed to investigate collagen protein expression after application of TETRAPEPTIDE-21. The results showed a significant increase in the amount of secreted collagen protein.

It also found that ECM marker genes were significantly induced after application of TETRAPEPTIDE-21.

This suggests that TETRAPEPTIDE-21 can be powerful in battling the effects of aging.

Improves Skin Elasticity

A study was performed on TETRAPEPTIDE-21’s effect on skin elasticity. After application of it twice a day for 8 weeks, skin volume, skin roughness and skin scaliness was evaluated.

The results were a reduction in skin scaliness and improvement in skin volume. The study also found that increased application of TETRAPEPTIDE-21 can decrease skin roughness.


A study to evaluate the anti-aging effects of TETRAPEPTIDE-21 was conducted. Application of TETRAPEPTIDE-21 occured twice a day for 8 weeks. The results showed effectiveness in reducing wrinkles and fine lines. Progress was visible after the first 4 weeks.

The study also found that TETRAPEPTIDE-21 can significantly boost collagen, hyaluronic acid and fibronectin. These are all great for improving skin elasticity and reducing skin roughness.

TETRAPEPTIDE-21, which is found in the Down To Earth Rejuvenating Peel Off Mask, has highly effective anti-aging effects. It can boost ECM proteins, improve skin elasticity and volume and reduce skin roughness and scaliness.

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